Alveoláris szarkóma rák, Legfrissebb anyagaink:

alveoláris szarkóma rák

Alveolar soft part sarcoma

Etymology[ edit ] The term alveolar comes from the microscopic pattern, visible during the analysis of slides of ASPS under the microscope in histopathology. The tumor cells seem to be arranged in the same pattern as the cells of the small air sacks alveoli in the lungs.

However, this is just a structural similarity. ASPS was first described and characterized in The fertilized egg divides and redivides forming a sphere.

Lágyrészdaganatok

Early in embryogenesis, dimples appear in the poles of the sphere and burrow through the sphere forming an inner passage that will ultimately form the gut. Malignancies arising from cells that were originally part of the outer alveoláris szarkóma rák of the sphere and those that were part of the embryonic tunnel are termed carcinomas; malignancies arising from the cells between the outer layer and the inner burrow are termed sarcomas.

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Causes[ edit ] Chromosomal analysis of ASPS shows the breaking and joining of two chromosomes in the tumor cells.

A piece of chromosome X breaks and is joined to chromosome Two sorts of fusions between chromosome X and chromosome 17 are found in different ASPS tumors: type one and type two.

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The resultant fusion protein ASPL — TFE3 is a rogue transcription factor that is the driver of aberrant cellular behavior including uncontrolled cell division and enhanced angiogenesis. Diagnosis[ edit ] High-magnification micrograph showing the characteristic large cells with abundant eosinophilic, i.

It can grow large and push aside surrounding tissues for a long time before causing any discomfort.

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Therefore, ASPS symptoms may either be a painless swelling, or a soreness caused by compressed nerves or muscles, affecting the range of motion in the area. Pathology[ edit ] The definitive diagnosis of ASPS is based on its appearance under the microscope i. ASPS' histomorphologic features include an alveolar-like pattern at low magnification and the presence of large cells with abundant eosinophilic cytoplasm and eccentric nuclei.

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Calcifications are commonly present, as may be seen with slow-growing neoplasms. Prognosis[ edit ] Although ASPS displays a relatively indolent course, the ultimate prognosis is poor and is often characterized by late metastases.

According to the American Cancer Societyabout alveoláris szarkóma rák cases of soft tissue sarcoma will be diagnosed in the USA in This predicts under new cases of ASPS.

Such low numbers of occurrence seriously impede the search for a cure by making it hard to gather any meaningful statistics about milyen férgek rendelkeznek az emberi kromoszómával disease. As a result, finding the best treatment option often involves making a lot of educated guesses. PMID January Rare Tumors.

Alveoláris szarkóma rák

PMC August July S2CID February Cancer Research. June Journal of Clinical Oncology. Current Opinion in Oncology.

Kezelési formák: Alveoláris szarkóma rák Lágy alveoláris szarkóma rák szarkóma kezelése A hagyományos orvoslás agresszív módszereket kínál a betegség kezelésére: kemoterápia, sugárzás, műtét. A hagyományos orvoslás alternatívájaként a népi jogorvoslatok kezelése. Ez a terápia nem okoz mellékhatásokat, és nem gyakorol agresszív negatív hatást az emberi testre.

December Cancer Cell.

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